I. Introduction to the Hospital

Matsumoto Ladies IVF Clinic was established in 1999 in Tokyo, Japan, by Dr. Yoshiko Matsumoto. It originally operated as Matsumoto Lady's Clinic in Minami-Ikebukuro. The clinic is part of the medical corporation Aicei Co., Ltd. It specializes in treatments for infertility and assisted reproductive technology services. The clinic holds certifications from JISART (Japan Assisted Reproductive Technology Standards Organization) and ISO9001 quality management system certification.

JISART certification is awarded to institutions specializing in infertility treatment through a standardized process involving peer review. The evaluation covers approximately 450 aspects, including technical skills, ethical standards, equipment requirements, personnel qualifications, and data transparency. According to JISART's information, there are only a few assisted reproductive medical institutions in Tokyo that have obtained this certification, and Matsumoto IVF Clinic is one of them.

Hospital Environment

II. Services Offered

1. Core Assisted Reproduction Services

Fertilization in vitro and intracytoplasmic sperm injection (ICSI):Based on the conditions of sperm and eggs, either in vitro fertilization or ICSI can be chosen. Piezo-ICSI, which uses piezoelectric pulses to assist sperm injection, reduces the stress and pressure on eggs caused by traditional mechanical procedures. This method requires high levels of expertise from both doctors and laboratories.

Preimplantation genetic testing (PGT-A):This technique uses NGS genome sequencing technology to screen blastocysts for chromosomal abnormalities before transplantation. It is suitable for cases where attempts at transplantation fail repeatedly, recurrent miscarriages, advanced age or decreased ovarian function, or when one partner has chromosomal abnormalities that affect reproduction.

Embryo Implantation Clinic:A specialized clinic for patients with repeated transplant failures. Services include EMMA endometrial microbiome analysis, CD138 staining tests (for chronic endometritis), ERA endometrial receptivity analysis, hysteroscopy examinations, Th1/Th2 immune balance testing, and thiotepone-based immunomodulatory therapy.

PFC-FD™ (Lyophilized Platelet-Rich Plasma):This product is made from autologous blood extracted from patients. It is lyophilized and processed by professional regenerative medicine institutions before being injected into the uterus. This treatment is suitable for patients who have difficulty achieving successful implantation or those whose endometrial environment requires further support.

Ovum Cryopreservation:Utilizes vitrification technology. Suitable for unmarried women, cancer patients who want to preserve their fertility before treatment, and those who wish to delay childbearing.

2. Complementary Treatment Services

Male Urology Clinic:Treatments are conducted by physicians qualified as experts in Japanese urology. Services include semen analysis, evaluation of male factors, and further examination and treatment for male infertility.

Traditional Chinese Medicine Therapy:Traditional Chinese medicine experts from the Japanese Tōyō Medical Association combine traditional Chinese medicine practices with modern infertility treatments. Treatments focus on regulating menstrual cycles, addressing coldness in the body, managing stress, and improving overall health.

Psychological Counseling Services:Provides professional psychological counseling to help alleviate psychological stress during the infertility treatment process, thereby helping patients build confidence.

3. Core Advantages

Based on a rigorous certification system, supported by extensive clinical experience, and characterized by specialized research in embryo implantation, we provide patients with standardized, personalized care that takes into account both physical and mental well-being.

This system covers five aspects: technical standards, ethical guidelines, personnel qualifications, equipment specifications, and data transparency. The laboratory environment and instruments are regularly reviewed by third parties, and treatment outcomes are made public.

Over two decades of clinical experience

Founded in 1999, this institution has been operating continuously. Since its establishment, it has successfully treated 11,712 patients (from 1999 to 2024). It offers a wide range of services and treatments.

Qualification system for embryo culture technicians

Embryo culture technicians must pass simulation training and meet internal standards for fertilization accuracy before they can work here. These standards are higher than those commonly used in the industry.

Highly qualified medical team

The medical team consists of doctors graduated from prestigious institutions such as the University of Tokyo, Tokyo Imperial Medical University, Shundai University, and Tohoku University. Many of them hold certifications such as Expert Physicians from the Japanese Obstetrics and Gynecology Society or Reproductive Medicine Experts from the Japanese Reproductive Medicine Association.

24/7 medical services

Patients can seek treatment before 18:30 on weekdays, as well as on weekends and holidays. This makes it easier for working patients to receive treatment without having to worry about scheduling issues.

Personalized ovulation induction plans

Plans are tailored based on factors such as age, AMH levels (ovarian reserve), and number of follicles. The focus is on egg quality rather than just quantity.

Treatment for both men and women, with multidisciplinary support

This clinic is equipped with advanced embryonic laboratories and related cultivation facilities. During the embryonic cultivation process, the following methods are used:Time-lapseContinuous monitoring is carried out through technical means, allowing for automatic imaging of the embryo every few minutes. This enables a complete record of the embryo's development from fertilization to blastocyst stage. This monitoring method eliminates the need to frequently retrieve the embryo, allowing for real-time observation of its development. It also reduces interference from external factors, providing accurate data for assessing the embryo's developmental potential and selecting the appropriate embryos for transplantation.

In terms of the management of the incubators, the clinic maintains stable temperature conditions and proper air circulation. Incubators are cleaned regularly, and all samples are carefully verified before use. In terms of genetic testing, the clinic is equipped with the necessary facilities for conducting tests.NGSGenome-wide analysis platform. For the preservation of fertility, vitrification freezing technology is used to preserve eggs and embryos.

In addition, this clinic also pays great attention to protecting patients' privacy. There are separate reception rooms, sperm storage areas, and dressing rooms designated for female patients.BIn areas like the super-rooms, the overall design of the clinic focuses on providing a comfortable environment and ensuring privacy.

The founder of this clinic proposed these principles when he first opened his practice."Ensure that patients fully understand and feel comfortable with undergoing infertility treatment."This concept is integral to every aspect of the clinic's operations, including communication during consultations, formulation of treatment plans, and organization of patient appointments. The clinic advocates this approach."Treat each ovulation induction procedure with caution, and approach each transplantation process with respect and reverence."It's important to maintain a scientific rational approach, along with a calm and patient attitude, while waiting for the future with uncertainty.